What do you use?

The Treason that is reason.

Yeah man...reason is awesome for making a template of music. These days they have some pretty cool refils, but generaly they suck. I like reason coz u dont need an external audiocard for creation. I use pro tools as a main prog and that has to stay as a desktop. I installed reason on my work PC and have been making little cheezy EBM and Trance tunes for over a year while 'working'.
I always use it for the drums, tho you need to pull them out when u want to do propper mixing and mastering...this can get time consuming and tedious.