I use Nuendo as my main DAW. I have to use Pro Tools at the studio, mostly because clients think its bad ass. So, we got a full Pro Tools HD setup there, with the Focusrite board and such, but for my personal studio, for my noise, Nuendo is central.
Along with other apps such as:
Synapse Audio's Orion, which is great for pattern based composing, utilizes its own set of instruments and fx, as well as VST and DirectX. Orion is favourite pet of mine, I'd say. Much preferred over Reason, AND it handles ReWire.
As far as stand alone waveform/sample editing, I use Soundforge, an early version, 4.5, as well as ver. 7. 4.5 was the last to utilize this freaking gnarly distortion algorithm, which I like. I also use Wavelab ver. 4. Mostly for applying fx or for mastering-type situations. Soundforge is my de facto stereo sound editor. Im quick in its environment.
Ableton Live I use sparingly, though its awesome. What its built for isnt quite in line with my composition, and what it does do well, I prefer doing "manually", through intense editing.
Also, Sony's ACID.
As for hardware, its quite mixed up. With my laptop I use a T.C. Electronics Konnekt 24D, with a PreSonus Digimax FS 8-channel pre. Along with this portable aspect of my rig, I also use a Universal Audio Solo-610 pre. I also use two a Universal Audio UAD cards; one is an Express card for the laptop, and a PCI for my box. With my box I use an Aardvark Q10.
For the desktop box I use an MOTU Midi Express 8X8, and an old MOTU Timepiece. Another of my boxes, an oldie, uses an AWE 64 Gold with a MOTU Micro express 4X6 (serial!). I use the first sequencer I bought, Cakewalk Professional 5, on that. Soundfont editor Vienna on that thing.
I've used trackers on and off over the years, ModPlug, Impulse, etc.
For outboard gear:
DBX: 1066 2-chan analog dynamics, DDP 2-chan digital dynamics;
Opera Digital KTV Master Link karaoke box, racked [for sick voice processing]
U.A. Solo-610 single channel pre
Empirical Labs: Distressor, Fatso
Fostex R-8 reel;
Korg: Z1, microkorg, Wavestation, TR-Rack;
Roland: MKS-30 Planet S, JP-8000, D-50, JD-800, GR-20 guitar synth;
Casio: CZ 101, CZ 5000, FZ-1 Sampler;
Akai: MPC 2000;
Novation: Supernova, K-Station;
Emu: Emulator II, Emulator E-5000 Ultra, Planet Phat, Morpheus;
For soft devices:
ReFX: all their shit. Plasticz is a personal favourite;
Izotope: all their stuff, also Ozone for media players. Phatmatik is an interesting sampler to use...
Luxonix: Ravity S and R, Purity;
Waldorf: PPG, Attack, D-Pole;
Virsyn: Cantor, Cube;
XLN: Addictive Drums;
Rob Papen: Albino;
LinPlug: Octopus, RM4;
Elemental Audio: Firium E.Q.;
...and a slew of free VST's, Destroy, Aries Code, Klanglabs, Psychic Mod, Digital Fish, etc. Then there's guitars and basses, drums and shit, but I've already belabored the topic, ey!?
Cool thread. Its nice to read about what everyone's using and digs. Especially so, since I know very few people who work with computer audio.